Antagonistic interactions drive host-virus evolutionary arms races, which often manifest as recurrent amino acid changes (i.e., positive selection) at their protein-protein interaction interfaces.Here, we investigated whether combinatorial mutagenesis of positions under positive selection in a host antiviral protein could enhance its restrictive pr
Automatic point-feature label placement (PFLP) is read more a fundamental task for map visualization.As the dominant solutions to the PFLP problem, fixed-position and slider models have been widely studied in previous research.However, the candidate labels generated with these models are set to certain fixed positions or a specified track line for
The paper analyzes the selection of Reich Ministers of Foreign chicago cubs earrings Affairs of the Weimar Republic and the peculiarities of its formation and evolution.It also makes a conclusion that during the period of the Weimar Republic the steps were taken to convert foreign ministry authorities from the closed to the open elite which sought
Burn injuries are unique in comparison to other types of trauma because of their severity and major systemic impact produced by extensive lesions with disfunctions that can persist even several years after the injury.Multiple complications can occur during burn injury evolution, from which infections are the most severe and the most frequently enco
HELLP syndrome is a pregnancy complication, putting at risk the life of mother and child, characterized by high blood pressure, elevated liver enzymes and low platelets.Serous retinal detachment is a rare complication of pregnancy and may be associated with HELLP syndrome.One of the most common symptoms is a decrease in visual acuity.A rare case of